Final Products of One-Electron Oxidation of Cyclic Dipeptides Containing Methionine Investigated by IRMPD Spectroscopy: Does the Free Radical Choose the Final Compound? - Université Paris-Saclay Access content directly
Journal Articles Journal of Physical Chemistry B Year : 2022

Final Products of One-Electron Oxidation of Cyclic Dipeptides Containing Methionine Investigated by IRMPD Spectroscopy: Does the Free Radical Choose the Final Compound?

Yining Jiang
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  • PersonId : 1246465
  • IdRef : 267117663
Carine Clavaguéra
Chantal Houée-Levin
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  • PersonId : 982589
E. Loire
Giel Berden
Debora Scuderi

Abstract

Reactive oxygen species (ROS) such as hydrogen peroxide (H2O2) and the hydroxyl radical (• OH) have specific functions in biological processes, while their uncontrolled production and reactivity are known to be determining factors in pathophysiology. Methionine (Met) residues act as endogenous antioxidants, when they are oxidized into methionine sulfoxide (MetSO), thus depleting ROS and protecting the protein.
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Dates and versions

hal-04089741 , version 1 (05-05-2023)

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Yining Jiang, Suvasthika Indrajith, Ariel Francis Perez Mellor, Thomas Bürgi, Marc Lecouvey, et al.. Final Products of One-Electron Oxidation of Cyclic Dipeptides Containing Methionine Investigated by IRMPD Spectroscopy: Does the Free Radical Choose the Final Compound?. Journal of Physical Chemistry B, 2022, 126 (48), pp.10055-10068. ⟨10.1021/acs.jpcb.2c06541⟩. ⟨hal-04089741⟩
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